Article ID Journal Published Year Pages File Type
6918233 Computer Methods in Applied Mechanics and Engineering 2013 16 Pages PDF
Abstract
► We combine bone cell population kinetics with multiscale bone mechanics. ► Preosteoblast proliferation and osteoclast differentiation are influenced by microstrains. ► Microstrains are determined from concentration relations of continuum micromechanics. ► Simulations of osteoporosis- and microgravity-driven bone loss agree well with experiments.
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Related Topics
Physical Sciences and Engineering Computer Science Computer Science Applications
Preview
Coupling systems biology with multiscale mechanics, for computer simulations of bone remodeling
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