Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6921122 | Computers in Biology and Medicine | 2015 | 6 Pages |
Abstract
Cranial nerve palsy caused by aneurysmal compression has not been fully evaluated. The main causes of symptoms are considered to be direct mechanical compression and aneurysm pulsations. Recent studies indicate that nerve dysfunction is mainly induced by pulsation rather than by direct compression, and successful cases of endovascular surgery have been reported. We describe a patient with an unruptured vertebral artery-posterior inferior cerebellar artery (VA-PICA) aneurysm compressing the facial nerve at the root exit zone (REZ). The patient presented with peripheral facial nerve palsy but not hemifacial spasm and was successfully treated by coil embolization. To investigate the mechanisms underlying peripheral facial nerve palsy, fluid structure interaction (FSI) analysis can approximate displacement and the magnitude of aneurysmal wall motion due to hemodynamic forces. In our case, maximum mesh displacement was observed at the aneurysmal wall attached to the facial nerve inside the pons rather than the REZ, which explains the clinical manifestation of facial nerve palsy in the absence of hemifacial spasm. This preliminary report demonstrates the utility of FSI analysis for investigating cranial nerve neuropathy.
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Tomoaki Suzuki, Hiroyuki Takao, Takashi Suzuki, Yukinao Kambayashi, Mitsuyoshi Watanabe, Kouichi Shinohara, Hidemoto Fujiwara, Shinji Nakazato, Masato Watanabe, Chiheb Dahmani, Makoto Yamamoto, Yukihiko Fujii, Yuichi Murayama,