Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6921137 | Computers in Biology and Medicine | 2015 | 9 Pages |
Abstract
A framework for the inflation of micro-CT and histology data using intravascular ultrasound (IVUS) images, is presented. The proposed methodology consists of three steps. In the first step the micro-CT/histological images are manually co-registered with IVUS by experts using fiducial points as landmarks. In the second step the lumen of both the micro-CT/histological images and IVUS images are automatically segmented. Finally, in the third step the micro-CT/histological images are inflated by applying a transformation method on each image. The transformation method is based on the IVUS and micro-CT/histological contour difference. In order to validate the proposed image inflation methodology, plaque areas in the inflated micro-CT and histological images are compared with the ones in the IVUS images. The proposed methodology for inflating micro-CT/histological images increases the sensitivity of plaque area matching between the inflated and the IVUS images (7% and 22% in histological and micro-CT images, respectively).
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Lambros S. Athanasiou, George A. Rigas, Antonis I. Sakellarios, Themis P. Exarchos, Panagiotis K. Siogkas, Katerina K. Naka, Daniele Panetta, Gualtiero Pelosi, Federico Vozzi, Lampros K. Michalis, Oberdan Parodi, Dimitrios I. Fotiadis,