| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6921206 | Computers in Biology and Medicine | 2015 | 11 Pages |
Abstract
This study assessed age-related diffuse myocardial fibrosis in two different age rat groups using quantitative texture analysis of high resolution ex-vivo late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) imaging. Results were compared with histological references. There was a significant increase of collagen fibers (%LV fibrosis) in the LGE CMR and contrast texture images of the elderly compared to the young group. Our results suggest that texture analysis may improve the assessment of subtle age-related myocardial fibrosis from LGE CMR images with a higher separability and increased SNR.235
Keywords
DTPAICMLGEDTIHSVGLCMECVROICMRNICMNon-Ischemic Cardiomyopathylate gadolinium enhancementCardiac magnetic resonancestandard deviationLeft ventricularTexture analysisdiffusion tensor imagingMagnetic resonance imagingDiethylenetriamine pentaacetic acidAgingsignal intensityextracellular volume fractionDiffuse myocardial fibrosisGray level co-occurrence matrixShort-axisregion of interestGadolinium
Related Topics
Physical Sciences and Engineering
Computer Science
Computer Science Applications
Authors
Pascale Beliveau, Farida Cheriet, Stasia A. Anderson, Joni L. Taylor, Andrew E. Arai, Li-Yueh Hsu,