Effects of two different levels of computerized decision support on blood glucose regulation in critically ill patients

► A CDSS integrated in a patient data management system in both levels, patient non-specific and patient specific, improved adherence to protocol with a larger effect at the patient specific level. ► The use of the CDSS at both levels, however, did not improve the quality of care as measured by our indicators. More research is needed to investigate whether socio-technical factors are at play. ► Statistical process control is a useful tool for monitoring the effect over time and captures within-institution significant and stable changes.