Article ID Journal Published Year Pages File Type
69375 Journal of Molecular Catalysis B: Enzymatic 2016 7 Pages PDF
Abstract

•Lipase-catalyzed kinetic resolution of γ-cyclogeraniol by Candida antarctica lipase B yielded 23% of optically pure (S)-γ-cyclogeraniol.•The first synthesis of lufferin-P was achieved.•The total synthesis of trixagol was achieved.•The absolute configuration of natural (+)-luffarin-P was determined to have an S configuration.•The facile synthetic route of β-alkyl-α,β-unsaturated butyrolactone was conducted from alkyl methyl ketone.

Lipase-catalyzed kinetic resolution of γ-cyclogeraniol by Candida antarctica lipase B yielded 23% of enantiomerically pure (S)-γ-cyclogeraniol. (+)-trixagol and (+)-luffarin-P were synthesized from the obtained (S)-γ-cyclogeraniol, and the absolute configuration of natural (+)-luffarin-P was determined to have an S configuration by our first synthesis of (S)-luffarin-P for the first time.

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Physical Sciences and Engineering Chemical Engineering Catalysis
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