Article ID Journal Published Year Pages File Type
69404 Journal of Molecular Catalysis B: Enzymatic 2015 6 Pages PDF
Abstract

•Three glycosides of tyrosol prepared by enzymatic transglycosidation.•Salidroside prepared in 6.7% yield.•Tyrosol β-galactoside prepared for the first time enzymatically in 10.9% yield.•Tyrosol α-galactoside prepared as a new substance in 32.2% yield.

For the purpose of synthesis of tyrosol β-d-glucopyranoside (salidroside) and its β-d- and α-d-galactopyranoside analogues, transglycosylation of tyrosol with fungal glycosidases (from Aspergillus niger and Aspergillus oryzae) was executed. Cellobiose, lactose and melibiose served as glycosyl donor giving 6.7% yield of salidroside, 10.9% of tyrosol β-d-galactopyranoside, and 32.2% of α-d-galactopyranoside. The glycosylations proceeded on the primary hydroxyl of the tyrosol.

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Physical Sciences and Engineering Chemical Engineering Catalysis
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