Creating smooth SI. B-spline basis function representations of insulin sensitivity

The 180 min 2nd Order B-spline BF provides a smooth second order continuous, more physiologically representative, and identifiable model of the dynamics of SI, and a more realistic resulting BG solution. The outcome provides a promising new addition to the ICING model and STAR GC protocol, while also opening up several new potential continuous time analyses of SI dynamics, not previously possible.