| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 69515 | Journal of Molecular Catalysis B: Enzymatic | 2015 | 8 Pages |
•Biotransformations of three prenylflavonoids have been investigated.•Total seven biotransformation products including six new ones were identified.•Their agonistic activities for PPAR γ were assayed.
Cunninghamella blakesleeana AS 3.0970 and AS 3.0910 and C. elegans AS 3.2028 were first used for biotransforming three major prenylflavonoids from Psoralea corylifolia, namely bavachinin, bavachin, and isobavachalcone. A total of seven biotransformation products, including six new compounds, were obtained and identified. The agonistic activities of peroxisome proliferator-activated receptor-γ against substrates and biotransformation products were also evaluated.
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