Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6982221 | Colloids and Surfaces B: Biointerfaces | 2015 | 42 Pages |
Abstract
- Glioblastoma treatment remains a challenge owing to the impermeability of BBB.
- Targeting of the drug to the glioma cells after transportation across BBB is a critical factor.
- PLNs are merged with the benefits of both polymeric nanoparticles and liposomes.
- The folic acid targeted polymer-lipid hybrid nanoparticles (PLNs) enhance BBB penetration.
- Encapsulated drug peptide conjugate was developed to subsequently target to the glioma cells.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Udita Agrawal, Gousia Chashoo, Parduman Raj Sharma, Ashok Kumar, Ajit Kumar Saxena, S.P. Vyas,