Article ID Journal Published Year Pages File Type
6982221 Colloids and Surfaces B: Biointerfaces 2015 42 Pages PDF
Abstract

- Glioblastoma treatment remains a challenge owing to the impermeability of BBB.
- Targeting of the drug to the glioma cells after transportation across BBB is a critical factor.
- PLNs are merged with the benefits of both polymeric nanoparticles and liposomes.
- The folic acid targeted polymer-lipid hybrid nanoparticles (PLNs) enhance BBB penetration.
- Encapsulated drug peptide conjugate was developed to subsequently target to the glioma cells.
Related Topics
Physical Sciences and Engineering Chemical Engineering Colloid and Surface Chemistry
Authors
, , , , , ,