| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7007115 | Chemical Engineering Research and Design | 2015 | 10 Pages |
Abstract
- A drug dissolution dynamics was integrated into a PBPK model.
- Parameter covariance was considered for more robust estimation.
- Proposed PBPK model had 73% less error than the model without drug dissolution dynamics.
- The proposed estimation scheme showed robust performance despite low signal-to-noise ratio.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Filtration and Separation
Authors
Dae Shik Kim, Jong Hwan Sung, Jong Min Lee,