| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 70082 | Journal of Molecular Catalysis B: Enzymatic | 2011 | 4 Pages |
Abstract
Organoselenium acetophenones oxidation using enzymatic reactions has been developed and chemoselectivity of phenylacetone monooxygenase (PAMO) with selenium-containing ketones has been explored. We discovered that this biocatalyst prefers selenium oxidation, which leads to selenoxide in excellent conversion, over Baeyer–Villiger oxidation.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► An enzyme-based approach to perform mild oxidation of selenium-containing ketones has been explored. ► The oxidation reactions catalyzed by PAMO were chemoselective. ► PAMO prefers selenium oxidation than Baeyer–Villiger oxidation. ► Several selenoxides were prepared using sodium periodate.
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Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Leandro H. Andrade, Eliane C. Pedrozo, Henrique G. Leite, Patrícia B. Brondani,