Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
702538 | Diamond and Related Materials | 2005 | 4 Pages |
Abstract
Here, we present a planar multi-patch-clamp-system based on a nano-crystalline diamond patch-membrane used for the investigation of ion channels in cell-membranes. In such a system the cell-membrane is electrically stimulated through a potential difference in the electrolyte across the patch-membrane. Usually, the patch-membrane material is a highly insulating dielectric. The use of diamond allows to add highly localized probes in close proximity to the clamping area for a localized analysis of the stimulation mechanism. The technological concept, realization and first electrical characteristics of the principle structure are discussed.
Related Topics
Physical Sciences and Engineering
Engineering
Electrical and Electronic Engineering
Authors
J. Kusterer, A. Alekov, A. Pasquarelli, R. Müller, W. Ebert, F. Lehmann-Horn, E. Kohn,