| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 70727 | Journal of Molecular Catalysis B: Enzymatic | 2009 | 9 Pages |
Abstract
Lipase catalyzed regio-selective acylation of five iridoid glycosides viz., picroside I&II, catalpol, agnuside and negundoside in the presence of various acyl donors such as vinyl acetate and p-nitrophenyl alkanoates was studied. The regio-selectivity of enzymatic acylation and yields were found to vary amongst different substrates. Monoacylated products were isolated with all the substrates under scrutiny indicating high regio-selective nature of such transformations. A series of acyl esters of picroside-I, picroside-II, catalpol, agnuside and negundoside have been synthesized by this enzymatic trans-esterification methodology.
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Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Parvinder Pal Singh, Naveed Ahmed Qazi, Syed Shafi, D. Mahendhar Reddy, Abid H. Banday, P. Bhaskar Reddy, K.A. Suri, B.D. Gupta, N.K. Satti, Basant P. Wakhloo, H.M. Sampath Kumar, G.N. Qazi,