| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 71071 | Journal of Molecular Catalysis B: Enzymatic | 2006 | 10 Pages |
Abstract
Biocatalysis offers a clean and ecological way to perform chemical processes, in mild reaction conditions and with high degree of selectivity. The use of enzymes, specially lipases, in organic solvents proves an excellent methodology for the preparation of single-isomer chiral drugs. This review covers some general aspects and representative examples of the use of lipases for the enantioselective or regioselective preparation of alcohol and amine intermediates in the synthesis of pharmaceuticals.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Vicente Gotor-Fernández, Rosario Brieva, Vicente Gotor,