| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 71211 | Journal of Molecular Catalysis B: Enzymatic | 2006 | 4 Pages |
Abstract
Enantioselective reductions of p-X-C6H4C(O)CH2N3 (X = H, Cl, Br, CH3, OCH3) mediated by Rhodotorula glutinis and Geotrichum candidum afforded the corresponding alcohols with complementary R and S configurations, respectively, in excellent yield and enantiomeric excesses. The obtained (R)-azidoalcohols are important starting materials for preparation of natural products and valuable pharmaceutical compounds such as (R)-Tembamide and (R)-Aegeline.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Catalysis
Authors
Lucídio C. Fardelone, J. Augusto R. Rodrigues, Paulo J.S. Moran,