Article ID Journal Published Year Pages File Type
71218 Journal of Molecular Catalysis B: Enzymatic 2006 5 Pages PDF
Abstract

A lipase-catalyzed procedure is described for the preparation of N-hydroxyalkylacrylamides useful among a number of electrophoretical applications such as capillary and gel electrophoresis. The N-hydroxyalkylacrylamides were prepared through an aminolysis reaction of alkanolamines on ethyl acrylate. The reaction was catalyzed by Candida antarctica lipase. The addition of radical inhibitors improved chemoselectivity and amides were obtained in high yield and purity at room temperature.

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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