| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7139084 | Sensors and Actuators B: Chemical | 2018 | 23 Pages |
Abstract
A novel optically active (E)-N'-(5-allyl-2-hydroxy-3-methoxybenzylidene) nicotinohydrazide (receptor 3) was synthesized by simple Schiff base condensation of 5-allyl-2-hydroxy-3-methoxybenzaldehyde with nicotinohydrazide. The ability of receptor 3 was investigated for the selective sensing of cations by chromogenic and fluorogenic technique. Receptor 3 showed highly selective response for Zn2+ ions in the binary mixture of acetonitrile/water (50:50, v/v) and possessed no interference from any of the potentially competing cations. Upon additions of Zn2+, the fluorescence intensity of the receptor 3 showed significant enhancement at 517â¯nm due to the chelation-enhanced fluorescence (CHEF) effect. The receptor 3 showed a good linearity for Zn2+ ion with the detection limit down to 4.35â¯nM. With negligible toxicity towards live cells, the receptor 3 could be successfully employed to monitor the Zn2+ ions in live A549 cells.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Manohar Patil, Shilpa Bothra, Suban K. Sahoo, Hilal Ahmad Rather, Rajesh Vasita, Ratnamala Bendre, Anil Kuwar,