Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7139798 | Sensors and Actuators B: Chemical | 2018 | 29 Pages |
Abstract
A simple fluorescent probe F-BH was designed and synthesized, introducing CN group which can be a recognition site for hypochlorous acid into the fluorescent probe molecule by using 2-benzothiazole hydrazone and formylated fluorescein. The fluorescence intensity of the probe F-BH solution was very weak, while the fluorescence of the solution was obviously enhanced and the color of the solution changed after the addition of ClOâ ion. The selection and competition experiments proved that the probe has great selectivity for recognition of hypochlorous acid over other ROSs/RNSs and anions. Fluorescence titration experiments show that the probe has a low detection limit (17.5â¯nM). The probe has been successfully applied to real-time detection of hypochlorous acid in Hela cells.
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Authors
Jie Li, Xiaopeng Yang, Di Zhang, Yongxiang Liu, Jun Tang, Yan Li, Yufen Zhao, Yong Ye,