Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7145872 | Sensors and Actuators B: Chemical | 2015 | 6 Pages |
Abstract
An electrochemical sensor for detection of diethylstilboestrol (DES) was successfully developed. At first, graphene-modified glassy carbon electrode (Gr/GCE) was fabricated by casting graphene (Gr) on the surface of the pretreated glassy carbon electrode (GCE). Then, gold nanoparticles (Nano-Au) were produced by reducing gold chloride tetrahydrate (HAuCl4) employing cyclic voltammetry (CV). Electrochemical behavior of DES at the graphene doped gold nanoparticle modified glassy electrodes (Gr/Nano-Au/GCE) was studied and a new method was developed for the electrochemical analysis of DES. Gr/Nano-Au/GCE showed a good catalytic performance for the electrochemical oxidation of DES in pH = 6.0 phosphate buffer solution (PBS). The oxidation peak currents of DES showed a linear relationship with their concentrations in the ranges of 1.20 Ã 10â8-1.20 Ã 10â5mol Lâ1. The estimated detection limit is 9.80 Ã 10â9 mol Lâ1. When the relative error is less than ±5%, no interference was found when detection was performed in the presence of some common ions, estradiol, estriol, estrone and folic acid. The modified electrode has good selectivity and stability and has been successfully applied to the detection of DES in food samples.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
Xinying Ma, Meifeng Chen,