Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7145935 | Sensors and Actuators B: Chemical | 2015 | 32 Pages |
Abstract
A new simple “off-on fluorescence type” chemosensor 1 (2-(N-(2-hydroxyethyl)-N-((pyridin-2-yl)methyl)amino)-N-(quinolin-8-yl)acetamide) has been synthesized for Zn2+. The sensor 1 comprises of the quinoline as fluorophore and the 2-((pyridin-2-yl)methylamino)ethanol as both binding site and water-soluble functional group. 1 showed a remarkable fluorescence enhancement in the presence of Zn2+ in aqueous solution, which was reversible with the addition of ethylenediaminetetraacetic acid (EDTA). The detection limit (0.02 μM) of 1 for Zn2+ is far lower than World Health Organization guideline (76 μM) in drinking water. Importantly, the chemosensor 1 could be used to detect and quantify Zn2+ in living cells and water samples. Moreover, the sensing mechanism was supported by theoretical calculations. Therefore, this sensor has the ability to be a practical system for monitoring Zn2+ concentrations in biological and aqueous samples.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Gyeong Jin Park, Hyun Kim, Jae Jun Lee, Yong Sung Kim, Sun Young Lee, Suyeon Lee, Insup Noh, Cheal Kim,