Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7147067 | Sensors and Actuators B: Chemical | 2014 | 6 Pages |
Abstract
This work reports a sensitive electrochemiluminescence (ECL) detection strategy based on Ru(bpy)32+/ordered mesoporous carbon/Nafion composite films modified glassy carbon electrode (GCE). Electrochemical and ECL behaviors of the prepared ECL sensors were studied with tri-n-propylamine (TPA) as coreactant. The proposed ECL sensor showed good reproducibility and high sensitivity to TPA with a wide linear range (4.75Â ÃÂ 10â9 to 6.25Â ÃÂ 10â4Â M) and low detection limit (1.58Â ÃÂ 10â9Â M). Under the optimized conditions, the ECL sensor with TPA as coreactant was employed to detect a neurotransmitter dopamine (DA), for estimating its practical application in the medicine analysis. The present sensor displayed a good response to the concentration of DA from 5.0Â ÃÂ 10â9Â M to 5.0Ã 10â4Â M. Moreover, the ECL sensor could be successfully applied to detect DA in real samples. The proposed signal amplification strategy for the preparation of ECL sensor could be easily attained and hold great promise for ultrasensitive medicine analysis.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Beina Wu, Chongchong Miao, Lili Yu, Ziyi Wang, Chusen Huang, Nengqin Jia,