Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7147491 | Sensors and Actuators B: Chemical | 2014 | 6 Pages |
Abstract
Partially phosphonated polyethylenimine (PEIP) has been developed as an easily functionalisable coating agent for iron oxide nanoparticles. Trypsin immobilization takes special advantage of the properties of this new material. Numerous enzymes can be loaded on the polymer by a covalent bounding with numerous amino groups. The PEIP contributes to the high stability of the material, through a strong covalent POFe bond. Resistance to hydrolysis and to temperature increasing ensure to obtain a highly recyclable magnetic nanomaterial designed for proteomic analysis.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Clément Monteil, Nathalie Bar, Richard Retoux, Joël Henry, Benoît Bernay, Didier Villemin,