Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7148074 | Sensors and Actuators B: Chemical | 2013 | 6 Pages |
Abstract
We report a rhodamine-based fluorescent probe (1) for cysteine (Cys). Masked with a para-hydroxybenzyl alcohol (HBA) unit, the probe's initial weak fluorescence is converted to strong fluorescence through a series of reactions of Michael addition and intramolecular cyclization of Cys, followed by deprotection of HBA. The caged probe (1) exhibits a selective and sensitive response toward Cys over homocysteine (Hcy) and glutathione (GSH) in HEPES buffer.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Soo-Yeon Lim, Doo-Ha Yoon, Do Yeon Ha, Jung mo Ahn, Dae Il Kim, Hyockman Kown, Hyun-Joon Ha, Hae-Jo Kim,