Hydrothermal synthesis of anatase titanium dioxide mesoporous microspheres and their antimicrobial activity

•Anatase TiO2 mesoporous microspheres was synthesized by a facile hydrothermal method.•The microspheres showed high surface area of 283 m2 g−1.•Dopant Fe was incorporated in the mesoporous microspheres.•The Fe doped microspheres exhibited improved antimicrobial activity.

We report here the synthesis of high surface area mesoporous microspheres of anatase titanium dioxide via nanoparticle assembly in a simple one pot hydrothermal reaction. The same procedure is applied to synthesize Fe-doped titanium dioxide mesoporous microspheres. The surface areas of the microspheres are as high as 283 m2 g−1. The antimicrobial activity of these microspheres is investigated against a broad range of Gram-negative and Gram-positive bacteria. The Fe-doped titanium dioxide microspheres exhibited improved antimicrobial activity against Mycobacterium smegmatis, Klebsiella pneumoniae, Staphylococcus aureus and Bacillus subtilis.

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