| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 73184 | Microporous and Mesoporous Materials | 2014 | 7 Pages |
•Synthesis cylindrical ordered-mesoporous silicon dioxide magnetic nanocarrier by double surfactant system.•Use infrared excitation fluorescent dye to demonstrate cells uptake process.•Use the nano-material load doxorubicin and get a nice drug release curve.•In vivo experiment show the material can be independently metabolized.
An MCM-41 type magnetic cylindrical ordered mesoporous silicon dioxide (M-COMSD) nanocarrier for targeted drug delivery has been synthesised. Pharmaceutical drug molecules have been loaded into the mesoporous framework of the M-COMSD. In vitro (Hale cells) and in vivo (mice) drug storage and release experiments of the nanocarrier have been performed. The results of the M-COMSD system demonstrate that this material could play a significant role in developing a new generation of controlled-release nanocarriers.
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