| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 73774 | Microporous and Mesoporous Materials | 2012 | 4 Pages |
The HKUST-1 metal–organic framework (MOF) was successfully applied as a biocidal material against representative yeast and mold. The synthesized MOF showed a strong antifungal effect against Saccharomyces cerevisiae for which the growth was completely inhibited, whereas the growth of Geotrichum candidum was reduced from 6.16 to 1.29 CFU mL−1. The antifungal action was related to copper ions released into the culture medium due to a progressive degradation of the crystalline structure of the material that involved the formation of surface extra-framework Cu(I). This study shows the potential of using copper-based metal–organic frameworks for a controlled release of biologically active copper ions.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Metal–organic framework with antifungal activity. ► Growth inhibition of yeast and mold. ► Slow MOF degradation producing extra-framework Cu(I). ► Controlled release of Cu ions.
