Article ID Journal Published Year Pages File Type
740394 Sensors and Actuators B: Chemical 2013 6 Pages PDF
Abstract

A boron-dipyrromethene (BODIPY) derivative with a hydroxymethyl group at the meso-position, 1, was synthesized, which exhibits a highly specific and rapid ‘turn-off’ response for HOCl during confocal fluorescence microscopy experiments under physiological conditions and in live cells. The formation of an electron-withdrawing formyl substituent upon oxidation results in highly efficient nonradiative decay of the S1 state and hence in a drastic decrease in fluorescence emission intensity.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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