Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
740394 | Sensors and Actuators B: Chemical | 2013 | 6 Pages |
Abstract
A boron-dipyrromethene (BODIPY) derivative with a hydroxymethyl group at the meso-position, 1, was synthesized, which exhibits a highly specific and rapid ‘turn-off’ response for HOCl during confocal fluorescence microscopy experiments under physiological conditions and in live cells. The formation of an electron-withdrawing formyl substituent upon oxidation results in highly efficient nonradiative decay of the S1 state and hence in a drastic decrease in fluorescence emission intensity.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Lizhi Gai, John Mack, Hui Liu, Zheng Xu, Hua Lu, Zhifang Li,