Article ID Journal Published Year Pages File Type
740709 Sensors and Actuators B: Chemical 2012 8 Pages PDF
Abstract

A new rhodamine derivative (Rh-D) was designed and synthesized, and its fluorescent behaviors toward various metal ions were investigated. Rh-D exhibits high selectivity and sensitivity in both absorbance and fluorescence detection of Hg2+ in methanol–water (30:70, v/v, pH 7.0, 20 mM HEPES buffer) medium. It was found that mercury ions coordinate reversibly to Rh-D and the spirolactam ring of Rh-D was opened, forming a 1:1 metal–ligand complex. In addition, fluorescence imaging experiments of Hg2+ in HL-7702 living cells demonstrated that its value of practical applications in biological systems.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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