Sensitivity of guided mode resonance filter-based biosensor in visible and near infrared ranges

The sensitivity of guided mode resonance filter (GMRF) biosensors was analyzed when the initial peak wavelength (IPW) changed from 400 to 1600 nm. The sensitivity of the GMRF to the sample refractive index and thickness was analyzed using rigorous coupled wave analysis method. Results indicate that for a certain IPW, the sensitivity of the GMRF did not change when the sample refractive index varied, but drastically decreased and achieved constant sensitivity with increased sample thickness. When the IPW increased, the sensitivity improved in relation to both sample refractive index and sample thickness. Furthermore, the capability of sample thickness improved with longer IPW. These results are helpful in obtaining an optimal GMRF biosensor.