| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 741433 | Sensors and Actuators B: Chemical | 2008 | 5 Pages |
Abstract
Recent advantages in electrophysiological technique on detecting potential and ion changes of taste cells make great progress in developing taste transduction mechanisms of taste receptor cells (TRCs). Light-addressable potentiometric sensor (LAPS) is used to detect extracellular potential of TRCs cultured on the silicon chip and to test the taste cell response to taste stimuli of NaCl, HCl, MgSO4, sucrose and glumate. Results show that the system composed of LAPS and TRCs is sensitive to gustatorius changes, which has great potential to monitor electrophysiology property of living TRCs. It is a novel non-invasive method to study taste transduction mechanisms in vitro for a long term.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Wei Zhang, Yan Li, Qingjun Liu, Ying Xu, Hua Cai, Ping Wang,