Article ID Journal Published Year Pages File Type
741700 Sensors and Actuators B: Chemical 2015 5 Pages PDF
Abstract

•The synthesis of novel Cu2O hollow nanospheres by stepwise controlling addition of the reducer.•Constructing a novel glucose sensing based on hollow Cu2O nanosphere–Nafion on GCE.•The sensing exhibits high sensitivity, low detection limit, and strong anti-interference property.•Hollow Cu2O nanospheres may be as excellent materials for non-enzyme electrochemical biosensor.

Utilizing as-prepared hollow cuprous oxide (Cu2O) nanospheres, a simple nonenzymatic glucose amperometric sensor was fabricated. The structure and morphology of hollow Cu2O nanospheres were characterized by transmission electron microscopy (TEM) and X-ray diffraction (XRD). Electrocatalytic activity of Cu2O was investigated by cyclic voltammetry (CV) and chronoamperometry, exhibiting a direct for the oxidation of glucose in an alkaline medium at 0.6 V. This constructing sensor was applied in detection of glucose with a detection limit of 0.41 μM, a linear detection range from 1.25 to 37.5 μM and with a high sensitivity of 2038.2 μA mM−1 cm−2. Due to superior catalytic performance and low cost of hollow Cu2O nanospheres, it shows great potential in applications for direct sensing of glucose.

Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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