| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 743137 | Sensors and Actuators B: Chemical | 2009 | 6 Pages |
Abstract
A fluorescent chemosensor, B2, for Hg2+ containing a BODIPY fluorophore and carboxyl-thiol metal-bonding moieties was described. B2 exhibits selective fluorescence enhancement (123-fold) toward Hg2+ over other metal ions. Especially, the fluorescence enhancement was unaffected by anions existing in environment and organism. B2 shows high sensitivity to Hg2+ in a concentration of ppb range with detection limit of 77 nM. B2-ester, the membrane-permeable ethyl ester, is able to be hydrolyzed to B2in vivo, and successfully applied to image intracellular Hg2+ in living cells.
Related Topics
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Authors
Jiangli Fan, Kexin Guo, Xiaojun Peng, Jianjun Du, Jingyun Wang, Shiguo Sun, Honglin Li,