| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 744340 | Sensors and Actuators B: Chemical | 2015 | 6 Pages |
In this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity.
Graphical abstractIn this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity.Figure optionsDownload full-size imageDownload as PowerPoint slide
