Designing a curved surface SPR device

A spherically curved surface plasmon resonance (SPR) surface is proposed theoretically and tested experimentally. The format achieves multi-angle SPR, where the angular modulation of the incident beam is performed by the geometrical shape of the SPR surface, not external to the sensor optics, thus achieving a robust compact design. The position of the imaged SPR band reflected from the surface is shown to be sensitive to adsorption of low-density lipoprotein (LDL) and exposure to nitrogen dioxide. Proposals for prototype sensors heads based on this concept are also shown.