Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
750997 | Sensors and Actuators B: Chemical | 2011 | 5 Pages |
Abstract
This paper describes a method for the selective retrieval of microparticles using bubbles generated by electrolysis. Microparticles (polystyrene beads, mouse embryos, and cell spheroids) were arrayed in microchambers fabricated in SU-8 on the surface of an electrode consisting of indium tin oxide (ITO) patterned on glass. Bubbles were selectively generated in a target microchamber by applying a voltage to electrodes positioned in the microchamber. As a result, we successfully retrieved microparticles (100 μm in diameter) positioned in the microchambers. This method is gentle enough to maintain cellular viability, and therefore, it will be a powerful tool for the quantitative analysis of cells in an arrayed system.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tomoaki Kurakazu, Kaori Kuribayashi-Shigetomi, Yukiko T. Matsunaga, Hiroshi Kimura, Teruo Fujii, Yasuyuki Sakai, Shoji Takeuchi,