| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 751248 | Sensors and Actuators B: Chemical | 2010 | 5 Pages |
Abstract
Detection of single base pair mutations in an unlabelled nucleic acid target sequence is demonstrated using the time-resolved measurement of the Förster Resonance Energy Transfer (FRET) between a long lifetime acridine-based fluorophore and a non-fluorescent quencher molecule covalently bound to a DNA Holliday junction-based nanoswitch.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Colin D. McGuinness, David Keszenman-Pereyra, Paul Dickinson, Colin J. Campbell, Beatrice A. Maltman, Till T. Bachmann, Peter Ghazal, Jason Crain,