β-Cyclodextrin incorporated carbon nanotube-modified electrode as an electrochemical sensor for rutin

An electrochemical sensor modified with multi-walled carbon nanotubes/β-cyclodextrin (MWNTs/β-CD) film was fabricated for the determination of rutin. The electrochemical behavior of rutin at the chemically modified electrode was investigated by cyclic voltammetry (CV). The response mechanism of MWNTs/β-CD film for rutin was based on the inclusion interaction of β-CD for rutin. The MWNTs/β-CD film showed preferably analytical performance characteristics in electrocatalytic oxidation and reduction for rutin compared with the MWNTs film and bare glassy carbon electrode (GCE). A linear calibration plot was obtained covering the range from 4.0 × 10−7 to 1.0 × 10−3 mol L−1 with a detection limit of 2.0 × 10−7 mol L−1. This electrochemical sensor showed excellent sensitivity, selectivity, stability and recovery for the determination of rutin in urine samples.