Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7518318 | Journal of Clinical Epidemiology | 2018 | 12 Pages |
Abstract
We made four recommendations for pragmatic trials to improve patient centeredness: (1) focus on superiority in effectiveness or safety, rather than noninferiority; (2) involve patients in specifying a priori subgroups; (3) report absolute measures of risk; and (4) complement intention-to-treat effect estimates with valid per-protocol effect estimates.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Public Health and Health Policy
Authors
Eleanor J. Murray, Ellen C. Caniglia, Sonja A. Swanson, Sonia Hernández-DÃaz, Miguel A. Hernán,