Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7518673 | Journal of Clinical Epidemiology | 2018 | 30 Pages |
Abstract
Group sequential trials can result in important reductions in the trial duration, which could make clinical trials more ethical by reducing the patients' exposure to noneffective treatments or by limiting their time on placebo.
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Authors
Ruben P.A. van Eijk, Stavros Nikolakopoulos, Toby A. Ferguson, Dawei Liu, Marinus J.C. Eijkemans, Leonard H. van den Berg,