Article ID Journal Published Year Pages File Type
7518984 Journal of Clinical Epidemiology 2018 9 Pages PDF
Abstract
Our study offers further evidence that two-stage approach generates estimates very similar as those from one-stage approach, even in the case of between-DB exposure heterogeneity and when several covariates must be concurrently considered. As current rules limit the free movement of electronic health data, our findings open the door of treating data within the country where they are generated and then to apply conventional techniques for summarizing estimates, which is the two-stage approach for meta-analysis using individual participant data.
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