Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7536230 | Revista Portuguesa de Cardiologia | 2018 | 21 Pages |
Abstract
In the past few years, significant advances have been made to clarify the genetic and molecular basis of these syndromes. A greater understanding of the underlying pathophysiological mechanisms showed the importance of the relationship between genotype and phenotype and led to progress in the clinical approach to these patients. However, it is still necessary to improve diagnostic capacity, optimize risk stratification, and develop new specific treatments according to the genotypeâphenotype binomial.
Keywords
Fibrilhação auricularTorsade de pointesCAV3TVPQTcTDPeefSBREVPDCCMSCCMDCNAICACardiomiopatia dilatadaSQTLTaquicardia ventricular polimórficaCa2+Fibrilhação VentricularINaNa+Cardiac arrhythmiasArritmias cardiacasEletrocardiogramaECGHeart diseasesTaquicardia ventricularmutationsSíndrome de BrugadaFrequência cardíacaMorte súbitaMorte súbita cardíacaCardiac sudden deathSingle nucleotide polymorphismSNPsodium channels
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Authors
Diana João Fonseca, Manuel Joaquim Vaz da Silva,