Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7553931 | Analytica Chimica Acta | 2018 | 29 Pages |
Abstract
A simple structured reaction-based probe for peroxynitrite (ONOOâ) was developed by using benzothiazole hydrazone base of the excited-state intramolecular proton transfer (ESIPT) dye. It was constructed from 2-hydrazinylpyridine and 3-(benzo[d]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde which possesses itself weak fluorescence and displayed prominent fluorescence response towards ONOOâ by oxidizes the C=N bond to an aldehyde in aqueous solution. The probe exhibited excellent selectivity and high sensivity towards ONOOâ with a low dectection limit of 5.8â¯Ãâ¯10â8â¯M in physiological condition. Moreover, the probe could realize fast recognition to ONOOâ in as short as 60â¯s. In addition, the probe was also successfully used for living cell imaging.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Youming Shen, Xiangyang Zhang, Youyu Zhang, Haitao Li, Lingcong Dai, Xinju Peng, Zhen Peng, Yingting Xie,