Article ID Journal Published Year Pages File Type
7553931 Analytica Chimica Acta 2018 29 Pages PDF
Abstract
A simple structured reaction-based probe for peroxynitrite (ONOO−) was developed by using benzothiazole hydrazone base of the excited-state intramolecular proton transfer (ESIPT) dye. It was constructed from 2-hydrazinylpyridine and 3-(benzo[d]thiazol-2-yl)-2-hydroxy-5-methylbenzaldehyde which possesses itself weak fluorescence and displayed prominent fluorescence response towards ONOO− by oxidizes the C=N bond to an aldehyde in aqueous solution. The probe exhibited excellent selectivity and high sensivity towards ONOO− with a low dectection limit of 5.8 × 10−8 M in physiological condition. Moreover, the probe could realize fast recognition to ONOO− in as short as 60 s. In addition, the probe was also successfully used for living cell imaging.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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