Article ID Journal Published Year Pages File Type
7556341 Analytica Chimica Acta 2013 8 Pages PDF
Abstract

- Dimethylation after guanidination (2MEGA) uses inexpensive reagents for isotopic labeling of peptides.
- 2MEGA can be optimized and automated for labeling peptides with high efficiency.
- 2MEGA is compatible with several commonly used cell lysis and protein solubilization reagents.
- The automated 2MEGA labeling method can be used to handle a variety of protein samples for relative proteome quantification.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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