Streamlining sample preparation and gas chromatography-tandem mass spectrometry analysis of multiple pesticide residues in tea

► We developed a new sample preparation method for the rapid analysis of pesticide residues in tea. ► QuEChERS-based extraction followed by LLE cleanup enabled good recoveries and minimisation of matrix co-extracts. ► Hydration of matrix is crucial for efficient extraction of target analytes. ► GC-MS/MS enabled simultaneous determination of target analytes.