| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7625926 | Journal of Pharmaceutical and Biomedical Analysis | 2018 | 23 Pages |
Abstract
The analytical mode performance was further tested after collecting Sprague Dawley rat plasma following a single-dose administration of chemotherapeutics or their association. The validated HPLC-DAD method allowed the simultaneous quantification of Gemcitabine and Irinotecan hydrochloride in the rat plasma, besides the evaluation of the pharmacokinetic parameters and drug delivery.
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Authors
L. Malatesta, D. Cosco, D. Paolino, F. Cilurzo, N. Costa, A. Di Tullio, M. Fresta, C. Celia, L. Di Marzio, M. Locatelli,