Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7753693 | Journal of Inorganic Biochemistry | 2018 | 27 Pages |
Abstract
Herein we present the study of the cytotoxic potential and apoptosis induction of a series of organoruthenium 8-hydroxyquinolinato complexes. Bromo substituted ligands gave best preliminary cytotoxicity results. Apoptosis induction results are in agreement with the cell viability assays. The most toxic compounds displayed IC50 values in the low micromolar range.50
Related Topics
Physical Sciences and Engineering
Chemistry
Inorganic Chemistry
Authors
Jakob Kljun, Ignacio E. León, Å pela PerÅ¡iÄ, Juan F. Cadavid-Vargas, Susana B. Etcheverry, Weijiang He, Yang Bai, Iztok Turel,