| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7764644 | Polyhedron | 2016 | 27 Pages |
Abstract
A mononuclear copper(II) complex [Cu(phen)(OH2)2(NO3)](NO3) (1) has been evaluated as model system for the catechol oxidase enzyme by using 3,5-di-tert-butylcatechol (DTBC) as the substrate in methanol medium, revealing that 1 exhibits greater catalytic activity with Kcat value 3.91Â ÃÂ 103Â hâ1. The complex cleaves the double strand of pBR 322 plasmid DNA in a concentration-dependent manner and is cytotoxic to the human hepatocarcinoma cell HepG2.67
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Authors
Dhananjay Dey, Subrata Das, Hare Ram Yadav, Anandan Ranjani, Loganathan Gyathri, Sanjay Roy, Partha Sarathi Guin, Dharumadurai Dhanasekaran, Angshuman Roy Choudhury, Mohammad Abdulkader Akbarsha, Bhaskar Biswas,