The versatility of pyridine-2,5-dicarboxylic acid in the synthesis of fac-M(CO)3 complexes (MÂ =Â Re, 99mTc): Reactivity towards substitution reactions and derivatization after coordination to a metal

Two new Re(I) tricarbonyl crystal structures are presented, fac-[NEt4][Re(2,5-PicoH)(CO)3(Br)] and fac-[NEt4][Re(2,5-PicoMe)(CO)3(Br)] and both illustrate a distorted octahedral arrangement. Methanol substitution kinetics is performed between fac-[NEt4][Re(2,5-PicoH)(CO)3(Br)] and various monodentate entering ligands. The functionalization on the backbone of the bidentate ligand is illustrated after the ligand is coordinated to the Re(I) metal center.