Syntheses, characterization, X-ray diffraction studies and in vitro antitumor activities of diorganotin(IV) derivatives of bis(p-substituted-N-methylbenzylaminedithiocarbamates)

Six new diorganotin(IV) complexes were prepared and investigated on the basis of CHNS, FT-IR, NMR and X-ray diffraction studies. Complex 1 crystallized in the triclinic P1¯ space group and complexes 2 and 6 crystallized in the monoclinic Cc and C 2/c space groups. The dimethyltin(IV) and dibutyltin(IV) compounds were evaluated for their in vitro antiproliferative activities against four different types of cells.